Nelio Flavoured Tablets Dogs x 10 Tablets (20mg x 10)

Uses 5mg - Treatment of congestive heart failure in dogs weighing more than 2.5 kg. 20mg - Treatment of congestive heart failure in dogs weighing more than 20 kg. Dosage and administration Oral administration: 0.23 mg of benazepril per kg bodyweight per day, equivalent to 0.25 mg of benazepril hydrochloride per kg bodyweight per day, as one administration, with or without a meal. In case of use of quarters or half tablets: Put the remaining quantity of the tablet back into the blister pocket and use for the next administration. The dose may be doubled, still administered once daily, if judged clinically necessary and advised by the veterinary surgeon. The tablets may be taken spontaneously by dogs, but can also be administered directly into the dog's mouth or be given with food if necessary. Contra-indications, warnings, etc Do not use in case of known hypersensitivity to ACE inhibitors or to any ingredient of the product. Do not use in any dog that has evidence of cardiac output failure, for example, due to aortic stenosis No evidence of renal toxicity to benazepril has been observed during clinical trials. However, as is routine in cases of renal insufficiency, it is recommended to monitor plasma urea and creatinine levels. At the start of the treatment, a decrease of the blood pressure and a transient increase of plasmatic concentrations of creatinine may occur. On rare occasions, transient signs of hypotension, such as lethargy and ataxia may occur. Studies in laboratory animals (rats) have shown embryotoxic effects (malformations of the fœtal urinary system) at doses not toxic for the mother. The safety of the medicinal product has not been studied in pregnant or lactating females. Do not use during pregnancy or lactation. Do not use in breeders. Interactions with potassium sparing diuretics, like spironolactone, triamteren and amiloride, can not be excluded. The concurrent administration of potassium-sparing diuretics should only be considered under regular monitoring of plasma potassium. The association of this product with other anti-hypertensive agents (e.g.: calcium channel blockers, β-blockers or diuretics), anaesthetics or sedatives may lead to additive hypotensive effect. In humans, the association of ACE inhibitors and NSAIDs can lead to reduced anti-hypertensive efficacy or impaired renal function. Therefore concurrent administration with NSAIDs or other medications with hypotensive effect should be considered with care. The concomitant administration of NSAIDs or ciclosporin requires a survey of the renal function.

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